Now showing items 1-11 of 11

    • Saitz Rojas, Waleska Lisette; Montero, David A.; Pardo, Mirka; Araya, Daniela; Fuente, Marjorie de la; Hermoso Ramello, Marcela Alejandra; Farfán Urzúa, Mauricio Javier; Ginard, Daniel; Rosselló Móra, Ramon; Rasko, Dave A.; Canto Fuentes, Felipe Antonio del; Vidal Álvarez, Roberto Mauricio (MDPI, 2022)
      Adherent-invasive E. coli (AIEC) is a pathotype associated with the etiopathogenesis of Crohn’s disease (CD), albeit with an as-yet unclear role. The main pathogenic mechanisms described for AIEC are adherence to epithelial ...
    • Landskron, Glauben; Fuente, Marjorie de la; Thuwajit, Peti; Thuwajit, Chanitra; Hermoso Ramello, Marcela (Hindawi Publishing, 2014)
      Acute inflammation is a response to an alteration induced by a pathogen or a physical or chemical insult, which functions to eliminate the source of the damage and restore homeostasis to the affected tissue. However, ...
    • Álvarez, Karin; Cassana, Alessandra; Fuente, Marjorie de la; Canales, Tamara; Abedrapo Moreira, Mario Antonio; López Köstner, Francisco (MDPI, 2021)
      Colorectal cancer (CRC) is the second most frequent neoplasm in Chile and its mortality rate is rising in all ages. However, studies characterizing CRC according to the age of onset are still lacking. This study aimed ...
    • Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriel; Vidal Álvarez, Roberto; Hermoso Ramello, Marcela (ELSEVIER, 2015)
    • Soongsathitanon, Jarupa; Jamjuntra, Pranisa; Sumransub, Nuttavut; Yangngam, Supaporn; Fuente, Marjorie de la; Landskron Ramos, Glauben Tamara; Thuwajit, Peti; Hermoso, Marcela Alejandra; Thuwajit, Chanitra (Hindawi, 2021)
      Signals from the tumor microenvironment (TME) have a profound influence on the maintenance and progression of cancers. Chronic inflammation and the infiltration of immune cells in breast cancer (BC) have been strongly ...
    • Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriela; Vidal Álvarez, Roberto; Hermoso Ramello, Marcela (Elsevier, 2014)
      Crohn’s disease (CD) is a multifactorial pathology associated with the presence of adherent-invasiveEscherichia coli (AIEC) and NLRP3 polymorphic variants. The presence of intracellular E. coli in otherintestinal pathologies ...
    • Céspedes, Sandra; Saitz Rojas, Waleska; Canto Fuentes, Felipe del; Fuente, Marjorie de la; Quera Pino, Rodrigo; Hermoso Ramello, Marcela; Muñoz, Raúl; Ginard, Daniel; Khorrami, Sam; Jorge, Girón; Assar Cuevas, Rodrigo; Rosello Mora, Ramón; Vidal Álvarez, Roberto (Frontiers Media, 2017)
      Adherent-invasive Escherichia coli (AIEC) strains are genetically variable and virulence factors for AIEC are non-specific. FimH is the most studied pathogenicity-related protein, and there have been few studies on other ...
    • Olivares Morales, Mauricio; Fuente, Marjorie de la; Dubois Camacho, Karen; Palominos Parada, Daniela Paz; Díaz Jiménez, David; Torres Riquelme, Alejandro; Xu, Xiaojiang; Chamorro Veloso, Nayaret; Naves, Rodrigo; González Burgos, María Julieta; Quera Pino, Rodrigo; Figueroa, Carolina; Cidlowski, John Anthony; Vidal, Roberto; Hermoso Ramello, Marcela (Frontiers Media, 2018)
      Crohn's disease (CD) is a chronic inflammatory bowel disorder characterized by deregulated inflammation triggered by environmental factors Notably, adherent-invasive Escherichia coli (AIEC), a bacterium with the ability ...
    • Fuente, Marjorie de la; MacDonald, Thomas T.; Hermoso Ramello, Marcela (Elsevier, 2015)
      IL-33, an IL-1 family member, is expressed by many cell types and can regulate gene transcription. IL-33 is released upon cell necrosis and the precursor form is enzymatically processed, and then drives inflammation as a ...
    • Hanus, Michelle; Parada Venegas, Daniela; Landskron Ramos, Glauben Tamara; Wielandt, Ana María; Hurtado, Claudia; Álvarez, Karin; Hermoso, Marcela Alejandra; López Köstner, Francisco; Fuente, Marjorie de la (Frontiers Media, 2021)
      Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other cancers, CRC is a multifactorial disease due to the combined effect of genetic and environmental factors. Most cases are sporadic, but a ...
    • Candia, Enzo; Díaz Jiménez, David; Langjahr, Patricia; Núñez, Lucía E.; Fuente, Marjorie de la; Farfán, Nancy; López Kostner, Francisco; Abedrapo Moreira, Mario Antonio; Alvarez Lobos, Manuel; Pinedo, George; Beltrán, Caroll J.; González, Carlos; González Burgos, María Julieta; Quera Pino, Rodrigo (2012)
      Toll-like receptor 2 (TLR2) is a type I pattern recognition receptor that has been shown to participate in intestinal homeostasis. Its increased expression in the lamina propria has been associated with the pathogenesis ...